Can I put a PCI-E x16 gpu in a PCI-E x16 slot?

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pcie 4 nvme in pcie 3 slot PCIe x16 devices are not compatible with smaller PCIe slots such as x1, x4, or x8 slots, but some motherboards may have PCIe x16 slots that are electrically

pciex4 slot Maybe you have a hair or something else blocking a contact in your PCIe slot Or a bent socket pin Or a defective motherboard Or a defective